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Medical-Pharma Biotech

Research Centers* in India-Ongoing Projects

All India Institute of Medical Sciences (AIIMS), New Delhi

Research: PhD and research in healthcare subjects.

Amity University, www.amity.edu

Andhra University ; Visakhapatnam; http://www.andhrauniversity.info.html

Anna University Gundi, Chennai. www.annauniv.edu

Research: Ph.D. and Research on Tissue Culture and Drug Discovery, Molecular Immunotechnology , Immunotechnology, Bio-organic and Computational Biology, Protein Biotechnology, Molecular Biology, Genetic Engineering and Molecular Biology, Bioprocess Engineering, Bioprocess Technology and Automation.

Banaras Hindu University (BHU) * Varanasi (UP)-221005. www.bhu.ac.in

Bharathidasan University , Tiruchirappalli, Tamil Nadu, 620024 www.bdu.ac.in

Research: PhD in Biochemistry, Bio-medical science, microbiology, Bioinformatics. Collaborated with several companies and funded by leading Indian and international funding agencies for research in plant Biotech and sericulture.

Cancer Research Institute, Tata Memorial Center, Parel, Mumbai- 400012, Maharashtra, Phone (O):022-4123803, Fax: 91-022-4146089, 4147365. www.tmc.gov.in.

Research: Research in cancer. An autonomous grant-in-aid institution of the Department of Atomic Energy (DAE), Government of India. PhD fellowships for Life science, Zoology, Biotech, Microbio and Biochem students.

Central Drug Research Institute (CDRI), Chattar Manzil Palace, Post Box No. 173, Lucknow - 226 001. http://www.cdriindia.org/home.asp

Research: Work under the aegis of CSIR. Works in the field of biomedical research where all the infrastructure and expertise are available to develop a drug, diagnostics and vaccines (related to reproductive health, malaria, filariasis, leishmaniasis, clinical trials & pharmacokinetics and preclinical safety evaluation & regulatory toxicity ) right from its concept to market using latest techniques and methodologies, to combat diseases prevalent particularly among Indian population. Offers PhD programmes. 

Centre for Research in Medical Entomology (CRME)

Research: An ICMR unit.

Centre JALMA Institute of Leprosy (CJIL), Agra

Research: An ICMR unit.

Council of Industrial Research (CSIR), Anusandhan Bhawan, Rafi Marg, New Delhi- 110 001, India. http://www.csir.res.in/. Fax: 011-23710618 (DG's Office). Phone: 011-23737889

Research: CSIR a premier industrial R&D organization in India constituted in 1942 aims to provide industrial competitiveness, social welfare, strong S&T base for strategic sectors and advancement of fundamental knowledge. It is one of the world’s largest publicly funded R&D organisations having linkages to academia, R&D organisations and industry. CSIR has 38 labs that knit India into a giant network adding quality to the life of each and every Indian and equally having Global Research Alliance. Of the 229 US patents granted in 2004-05 to Indian inventors (excluding foreign assignees), CSIR has 140 (61.1%). It provides financial support to the public and private institutes on basic and applied research projects.

Enterovirus research centre (EVRC), Mumbai.

Research: An ICMR unit.

Food and Drug Toxicology Research Centre (FDTRC), Pune

Research: An ICMR unit engaged in drug research.

ICMR-NIC Centre for Biomedical  Information

Indian council of Medical Research (ICMR)

Indian Industrial Toxicology Research Centre, Post Box No. 80, Mahatma Gandhi Marg, Lucknow - 226 001, India
Phone (Director's Office): +91-522-2621856, 2628227, 2613357. http://www.iitrindia.org/.

Research: Indian Institute of Toxicology Research (IITR) (formerly: Industrial Toxicology Research Centre), is a constituent laboratory of CSIR. It studies the impact of industrial and environmental chemicals on human health and ecosystem, and environmental monitoring of pollutants in air, water and soil. The institute also helps regulatory bodies to formulate/amend guidelines for safe use of chemicals or products. Major research areas are Analytical Chemistry, Aquatic toxicology, Biomembrane Toxicology, Cardiovascular Toxicology, Cell Biology, Developmental Toxicology, Dyes & Food Adulterant Toxicology, Ecotoxicology, Embryotoxicology , Environmental Biotechnology , Environmental Carcinogenesis, Environmental Chemistry &  Waste Water Analysis, Environmental Microbiology, Environmental Monitoring, Epidemiology, Fibre Toxicology, Herbal Research, Immunobiology, Immunotoxicology, Inhalation Toxicology, Neurotoxicology, Pesticides Toxicology, Petroleum Toxicology, Photobiology, Preventive Toxicology, Proteomics, Safety Evaluation of GM-Drugs, Toxicokinetics, Toxicogenomics & Predictive Toxicology.

Indian Institute of Chemical Biology (IICB), 4, Raja S.C. Mullick Road, Kolkata-700 032, West Bengal, India. Phone : +91 33 2473 0492. Fax : +91 33 2473 5197, +91 33 2472 3967. E-Mail : director@iicb.res.in. http://www.iicb.res.in/ 

Research: A unit of CSIR. Research work done in Cell Biology & Physiology, Chemistry, Molecular & Human Genetics, Infectious Diseases, Drug Development / Diagnostics & Biotechnology and Structural Biology & Bioinformatics. Developed bioinformatics programmes (GCA & Clusterviz for clustering protein and gene sequencing), SPAT- software tool for nucleotide and amino acid substitution study, study Homology Modeling, Delph, Biopolymer, DOCKING; cardiac disfunction and hormones, neurological disorder, stem cell and corneal implantation, sperm motility, visceral leishmaniasis. It’s molecular and Human genetics division aims to understand the molecular genetic basis of diseases common in Indian populations (haemophilia, glaucoma, Wilson disease, and oculo-cutaneous albinism), genetic damage due to arsenic, antimutagenic and anticarcinogenic effects of black tea polyphenols, study gene expression and function in pathogenic microorganisms (V.cholerae, Leishmania), DNA Vaccine against leishmaniasis, programmed cell death and to develop transgenic plants for pest resistant & improved  pharmaceutical/nutraceuticals. Offers PhD programmes.  

Indian Institute of Integrative Medicine(IIIM), (formerly Regional research laboratory), Canal Road, Jammu Tawi - 180 001. Phone: 2569111, 2569222; Fax: 2569333 STD Code: 0191. http://rrljammu.org/index1.htm

Research: A unit of CSIR. Its R&D units consist of Biotech, pharmacology and natural product chemistry. Its biotech section has facility of pilot plant, with Micro-processor controlled fomenters (1- 4,000 liter capacity), and state-of–art equipment required for Microbiology, Bio-Chemistry, Enzymology, Genetic Engineering and Bio-Chemical Engineering. isolation of microbes, their identification (by both conventional as well as molecular markers), characterization, -preservation and screening for specific microbial enzymes and secondary metabolites are carried out. The microbial strains encoding such enzymes are identified up to species level by 16S rRNA gene typing. The specific enzymes are purifiedto homogeneity using FPLC. Terminal sequencing is undertakenfor designing the primers for the location & cloning of desired gene(s). Selected wild type and recombinant strains are grown at lab to pilot scale fermentors.The strategies of scale-up or scale-down are selected depending upon the nature of the process under study. The pilot plant is well equipped for down stream processing of the microbial biomass for the isolation of desired biomolecules/products. The Molecular biology and Genetic Engineering laboratories are well equipped to undertake gene cloning, heterologous expression, sequencing, RACE and RTPCR of selected genes. The lab has ABI 310 automated DNA sequence and Shimadzu automated N-terminal protein sequencer for amino acid sequencing. The lab is also well equipped to undertake plant molecule-based biopotentiator molecules for enhancing the effect of anti-bacterial and anti-fungal drugs. Its Natural Product chemistry division has Research and Development in the area of (i) herbal drugs, drug formulation and end-to-end technology on medicinal plants (ii) isolation of bioactivity guided extracts, fractions and new molecules (iii) standardization, quality control and isolation of marker compounds (iv) process development and upscaling of technologies for value added phytochemicals and phytopharmaceuticals and chemistry of essential oil bearing plants and their value added products. In the Pharmacology division the plant based products (extracts/fractions/pure principles) are subjected to battery of well established in vitro as well as in vivo tests for their Biopotential, efficacy and biosafety. The spectrum of bioactivities is mainly focussed in areas, like Bioenhancer and bioavailability, Hepatoprotective, Anticancer, Antidiabetic, Antiinflammatory & antiarthritis, Immunomodulatory, General pharmacological and Transgenic animals for pharmacogenomics.

Indian Institute of Science (IISC), Bangalore.

Research: Genetic Engineering, biochemistry, microbiology, cell biology. Offers PhD programmes.

Indian Toxicology Research Centre (ITRC), Lucknow

Institute for Research in Reproduction (IRR), Mumbai

Research: An ICMR unit.

Institute of Child Health and Hospital for Children

Institute of cytology and preventive oncology (ICPO), Delhi.

Research: An ICMR unit.

Institute of Genomics and Integrative Biology (IGIB), Near Jubilee Hall, Mall Road, Delhi-110 007, Ph. No. 91-011-27666156/157, 27667602, 27667439. Fax:91-011-27667471. Email: info@igib.res.in, www.igib.res.in/

Research: Its a CSIR Unit. It carries out research on areas of modern biotechnology and biological sciences such as allergy and infectious diseases, molecular pathogenesis and recombinant DNA technology via Genomics and Bio-informatics. In collaboration with major tertiary referral centers and through genome sequence and polymorphism analysis, IGIB is using all the tools of Functional Genomics (like SNP, Microarray technology, mitochondrial chip, toxicogenomics) towards understanding the molecular basis of complex disorders like schizophrenia, neurological disorders, diabetes, asthma, high altitude sickness, infectious diseases etc. IGIB undertakes design & synthesis of nucleic acids and bioactive peptides required for several biomedical applications, to understand their role in various neurological diseases and hypertension. Significant achievement of IGIB in this area is designing and synthesizing a library of peptidomimics for Angiotensin converting enzyme (ACE) inhibitor. It’s also working on Development of Biochips for biomedical applications and synthesis and conformational studies of photo responsive oligonucleotides. Its comparative genomics & gene expression profiling programmes mainly involve exploration and exploitation of microbial wealth of India for novel com pounds and bio-transformation process, and establishing advanced facility for safety evaluation of genetically modified/engineered drugs. It works on   Asthma, Tuberculosis and Aspergillosis and carries out work on screening plant, microbial, fungal and insect extracts for evaluation of antibacterial, anti-inflammatory and anti-fungal activities. It has signed MoU with several institutes and company in India and abroad to carry out collaborative research.

Institute of Imunohaematology (IIH), Mumbai.

Research: An ICMR unit.

Institute of Liver and Biliary Sciences, Delhi

Institute of Microbial Technology, Sector 39-A, Chandigarh, Pin- 160036. PH: +91-172-2695215, 2695225, 2636680 – 94.  www.imtech.res.in.

Research: A unit of CSIR. Molecular Biology: Molecular biology of pathogens, gene silencing, stress tolerance, signal transduction, gene expression, genome-wide analysis. Cell Biology & Immunology: Host- pathogen interactions, TB vaccine development, T- and B-cell activation, infectious agents & vaccine targets, cell structure & microscopy. Protein Science & Engineering: Structure-function relationships, design, expression, structural analysis and modeling, crystallization, structure determination and structure- based drug designing Applied & Environmental Microbiology: Microbial diversity, environmental biotechnology, biotransformations, vaccines, extremophiles and their metabolites. Bioinformatics: Computer-aided vaccine and drug development, genome annotations, protein structure prediction, molecular simulations. Bioorganic Chemistry: Enzymes and abzymes in organic synthesis, biocatalysis and bioactive molecules. Peptide Chemistry: Peptide synthesis, conformational characterization and modelling.  Biochemical Engineering: Fermentation & downstream processing, process development, bioreactor modelling and control. Biosensors: Immunodiagnostics of pesticides and other environmental pollutants based on bioprobe-electronic interfacing. Offers PhD program.

Institute of Pathology (IOP), Delhi.

Research: An ICMR unit.

International Centre for Genetic Engineering and Biotechnology (ICGEB), New Delhi.

Research: Offers PhD programmes.

Jamia Millia Islamia, New Delhi.  

Kidwai Memorial Institute of Oncology (KMIO)

Lala Ram Swarup Institute of Tuberculosis and Respiratory Diseases

Mahatma Gandhi Institute of Medical Sciences

Research: Biochemistry

Malaria Research Centre (MRC), Delhi

Research: An ICMR unit.

National AIDS Research Centre (NARI), Pune

Research: An ICMR unit.

National Brain Research Centre (NBRC)

Research: Offers PhD programmes.

National Centre for Cell Sciences (NCCS)

Research: Offers PhD programmes.

National Institute of Cholera and Enteric Diseases, Division of Virology (NICED), Kolkata.

Research: An ICMR unit.

National Institute of Communicable Disease (NICD), Directorate General of Health Services, Ministry of Health and Family Welfare (GOI), 22, Sham Nath Marg, New Delhi-110 054 www.nicd.org.htm

National institute of epidemiology (NIE), Chennai.

Research: An ICMR unit.

National Institute of Immunology (NII), Aruna Asaf Ali Marg, New Delhi-110067.

Research: Offers PhD programmes.

National Institute of Mental Health and Neuro Sciences (NIMHANS)

National Institute of Naturopathy (NIN)

National institute of nutrition (NIN), Pune.

Research: An ICMR unit.

National Institute of Occupational Health (NIOH), Ahmedabad.

Research: An ICMR unit.

National Institute of Virology (NIV), Pune.

Research: An ICMR unit. Research on viral diseases.

National Research Centre on Equines (NRCE)

National Research Centre on Yak (NRCYAK)

National Tuberculosis Institute (NTI), Directorate General of Health Services, ‘AVALON’ No.8, Bellary Road, Bangalore 560 003. Phone: 3441192, 3441193, 3447951. E-mail:ntiindia@blr.vsnl.net.in

Research: Provide training to NGOs and Private Practitioner’s. As NTI is a collaborative center, WHO fellows are trained as & when the request are made.

Postgraduate Institute of Medical Education and Research Experimental Medicines

Research: Immunopathology and Biochemsitry

Rajendra Memorial Research Institute of Medical Sciences (RMRIMS), Patna.

Research: An ICMR unit.

Tamil Nadu Dr. M.G.R. Medical University

Tuberculosis Research Centre (TRC), Chennai

Research: An ICMR unit.

University of Madras, Tamil Nadu.

Research: Research in Protein Research and Biomedical Genetics. Accredited by NAAC at five star level.

 

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